Home / Recipes / Antisera ๐ How to Make Antisera in Infinite CraftAntisera is a long haul. Even on the shortest known route it takes 36 combinations to get there, and the final one is Antigen plus Similar. Expect to build several intermediate elements you will never use again.
The final combination
๐งฌ Antigen+ ๐ Similar= ๐ Antisera
Marathon 36 steps from the base elements ยท crafting depth 59 ยท 2 known recipes
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What is worth knowing At 36 steps it is longer than 97% of solved elements, which puts it in our marathon band. Only 2 known combinations produce Antisera, so there is very little room to improvise. Follow the path exactly. Its crafting depth of 59 is unusually deep. Depth counts the longest chain needed to reach it, and most elements people search for sit well below this. Full crafting path from the base elements Start with Water, Fire, Wind and Earth, then follow these 36 combinations in order.
1 ๐ Earth+ ๐จ Wind= ๐ซ๏ธ Dust2 ๐ Earth+ ๐ง Water= ๐ฑ Plant3 ๐ซ๏ธ Dust+ ๐ฑ Plant= ๐ฑ Pollen4 ๐ฑ Pollen+ ๐จ Wind= ๐คง Allergy5 ๐ฑ Plant+ ๐ง Water= ๐ Swamp6 ๐ฅ Fire+ ๐ Swamp= ๐ Dragon7 ๐ Dragon+ ๐ซ๏ธ Dust= ๐ Dragonfly8 ๐ Dragonfly+ ๐ Earth= ๐ Ant9 ๐ Ant+ ๐ Dragonfly= ๐ Antfly10 ๐คง Allergy+ ๐ Antfly= ๐ฆ Antibody11 ๐ฑ Plant+ ๐จ Wind= ๐ผ Dandelion12 ๐ผ Dandelion+ ๐ง Water= ๐ท Wine13 ๐จ Wind+ ๐ท Wine= ๐ Balloon14 ๐ Balloon+ ๐ซ๏ธ Dust= ๐ฐ Dust Bunny15 ๐ซ๏ธ Dust+ ๐ฅ Fire= ๐ Ash16 ๐ Ash+ ๐ฅ Fire= ๐ฅ Phoenix17 ๐ Dragon+ ๐ฅ Phoenix= โฏ๏ธ Yin Yang18 ๐ฐ Dust Bunny+ โฏ๏ธ Yin Yang= ๐ Opposite19 ๐ฆ Antibody+ ๐ Opposite= ๐งฌ Antigen20 ๐ฅ Fire+ ๐ง Water= ๐จ Steam21 ๐ฅ Fire+ ๐จ Steam= ๐ Engine22 ๐ผ Dandelion+ ๐ Engine= ๐ Helicopter23 ๐ Earth+ ๐ Earth= ๐๏ธ Mountain24 ๐ Helicopter+ ๐๏ธ Mountain= ๐ Rescue25 ๐ Ant+ ๐ Rescue= ๐ Aid26 ๐ซ๏ธ Dust+ ๐จ Wind= ๐ช๏ธ Sandstorm27 ๐ช๏ธ Sandstorm+ ๐ง Water= ๐๏ธ Oasis28 ๐๏ธ Oasis+ ๐ฑ Plant= ๐ Date29 ๐ Date+ ๐ง Water= ๐ Dating30 ๐ Earth+ ๐จ Steam= ๐ฉ Mud31 ๐ฅ Fire+ ๐ฉ Mud= ๐งฑ Brick32 ๐งฑ Brick+ ๐งฑ Brick= ๐งฑ Wall33 ๐ Dating+ ๐งฑ Wall= ๐ฌ Facebook34 ๐ฌ Facebook+ ๐ฅ Fire= ๐ Like35 ๐ Aid+ ๐ Like= ๐ Similar36 ๐งฌ Antigen+ ๐ Similar= ๐ AntiseraCrafting tree 1 Earth + Wind โ Dust 2 Earth + Water โ Plant 3 Dust + Plant โ Pollen 4 Pollen + Wind โ Allergy 5 Plant + Water โ Swamp 6 Fire + Swamp โ Dragon 7 Dragon + Dust โ Dragonfly 8 Dragonfly + Earth โ Ant 9 Ant + Dragonfly โ Antfly 10 Allergy + Antfly โ Antibody 11 Plant + Wind โ Dandelion 12 Dandelion + Water โ Wine 13 Wind + Wine โ Balloon 14 Balloon + Dust โ Dust Bunny 15 Dust + Fire โ Ash 16 Ash + Fire โ Phoenix 17 Dragon + Phoenix โ Yin Yang 18 Dust Bunny + Yin Yang โ Opposite 19 Antibody + Opposite โ Antigen 20 Fire + Water โ Steam 21 Fire + Steam โ Engine 22 Dandelion + Engine โ Helicopter 23 Earth + Earth โ Mountain 24 Helicopter + Mountain โ Rescue 25 Ant + Rescue โ Aid 26 Dust + Wind โ Sandstorm 27 Sandstorm + Water โ Oasis 28 Oasis + Plant โ Date 29 Date + Water โ Dating 30 Earth + Steam โ Mud 31 Fire + Mud โ Brick 32 Brick + Brick โ Wall 33 Dating + Wall โ Facebook 34 Facebook + Fire โ Like 35 Aid + Like โ Similar 36 Antigen + Similar โ Antisera
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Other ways to make Antisera 2 combinations are known to produce Antisera. Here are 2 of them.
Antisera at a glance
Steps to craft 36 Marathon
Crafting depth 59 longer than 97% of solved elements
Known recipes 2 ways to make it
Used in 0 other combinations Other elements that take 36 steps Similar effort to Antisera, if you want something else to chase.
Frequently asked questions How do you make Antisera in Infinite Craft? Combine Antigen with Similar. The full path from the base elements takes 36 steps.
How many steps does it take to make Antisera? 36 steps on the shortest known path from Water, Fire, Wind and Earth.
Is Antisera hard to make in Infinite Craft? It rates as marathon. At 36 steps it is longer than 97% of solved elements.
Is there more than one way to make Antisera? Yes. 2 combinations are known to produce Antisera, and the shortest route is shown above.
Path verified against the open recipe graph on 2026-10-23 . Method described in our methodology , data credited on data sources .