Home / Recipes / Nucleotide 𧬠How to Make Nucleotide in Infinite CraftNucleotide is a long haul. Even on the shortest known route it takes 61 combinations to get there, and the final one is Letters plus Nucleophile. Expect to build several intermediate elements you will never use again.
The final combination
π€ Letters+ π΅ Nucleophile= 𧬠Nucleotide
Marathon 61 steps from the base elements Β· crafting depth 101
π Copy steps
What is worth knowing At 61 steps it is longer than 100% of solved elements, which puts it in our marathon band. Its crafting depth of 101 is unusually deep. Depth counts the longest chain needed to reach it, and most elements people search for sit well below this. Full crafting path from the base elements Start with Water, Fire, Wind and Earth, then follow these 61 combinations in order.
1 π Earth+ π§ Water= π± Plant2 π Earth+ π± Plant= π³ Tree3 π³ Tree+ π§ Water= π River4 π River+ π³ Tree= π Paper5 π Paper+ π± Plant= π Book6 π Earth+ π River= β¬οΈ Delta7 π Book+ β¬οΈ Delta= π Alphabet8 π± Plant+ π¨ Wind= πΌ Dandelion9 π₯ Fire+ π₯ Fire= π Volcano10 πΌ Dandelion+ π Volcano= π Fireworks11 π Alphabet+ π Fireworks= π€ Letters12 π¨ Wind+ π¨ Wind= πͺοΈ Tornado13 πͺοΈ Tornado+ π§ Water= π Tsunami14 πͺοΈ Tornado+ π Tsunami= π₯ Destruction15 π Earth+ π₯ Fire= π Lava16 π Lava+ π§ Water= πͺ¨ Stone17 π Lava+ πͺ¨ Stone= πͺ Obsidian18 π₯ Destruction+ πͺ Obsidian= πΉ Nether19 π§ Water+ π§ Water= π Lake20 π Earth+ π Earth= ποΈ Mountain21 π Lake+ ποΈ Mountain= ποΈ Fjord22 π§ Water+ π¨ Wind= π Wave23 π Earth+ π Wave= ποΈ Sand24 ποΈ Sand+ π§ Water= ποΈ Beach25 ποΈ Beach+ π Lava= πΊ Hawaii26 πΊ Hawaii+ π¨ Wind= πΊ Hula27 πΊ Hula+ π§ Water= π Hula Hoop28 π± Plant+ π Wave= π Seaweed29 πΊ Hawaii+ π Seaweed= π Poke30 π± Plant+ π Poke= π Pokemon31 π Hula Hoop+ π Pokemon= π Hoopa32 ποΈ Fjord+ π Hoopa= π Unown33 πΉ Nether+ π Unown= π N34 π Earth+ π¨ Wind= π«οΈ Dust35 π Lake+ π± Plant= πΈ Lily36 π«οΈ Dust+ πΈ Lily= πΌ Angel37 π₯ Fire+ π§ Water= π¨ Steam38 π₯ Fire+ π¨ Steam= π Engine39 π Engine+ π± Plant= π Car40 π Car+ π Car= π Truck41 πΌ Angel+ π Truck= π¦ UPS42 π Engine+ π¨ Steam= π Train43 π Train+ π¨ Wind= π¨ Zephyr44 β¬οΈ Delta+ π¨ Zephyr= ΞΆ Zeta45 π¦ UPS+ ΞΆ Zeta= π
Upsilon46 π N+ π
Upsilon= β Nu47 π₯ Fire+ π¨ Wind= π¨ Smoke48 π¨ Smoke+ π§ Water= π«οΈ Fog49 π«οΈ Dust+ π«οΈ Fog= π«οΈ Smog50 π₯ Fire+ π«οΈ Smog= π«οΈ Pollution51 π«οΈ Pollution+ π§ Water= π Acid52 π Acid+ π River= π PH53 π Lake+ π§ Water= π Ocean54 π Ocean+ π§ Water= π Fish55 π± Plant+ π¨ Smoke= π―οΈ Incense56 π Earth+ ποΈ Fjord= π Land57 π―οΈ Incense+ π Land= πΏ Sage58 π Fish+ πΏ Sage= π§ Philosopher59 π PH+ π§ Philosopher= Ξ¦ Phi60 β Nu+ Ξ¦ Phi= π΅ Nucleophile61 π€ Letters+ π΅ Nucleophile= 𧬠NucleotideCrafting tree 1 Earth + Water β Plant 2 Earth + Plant β Tree 3 Tree + Water β River 4 River + Tree β Paper 5 Paper + Plant β Book 6 Earth + River β Delta 7 Book + Delta β Alphabet 8 Plant + Wind β Dandelion 9 Fire + Fire β Volcano 10 Dandelion + Volcano β Fireworks 11 Alphabet + Fireworks β Letters 12 Wind + Wind β Tornado 13 Tornado + Water β Tsunami 14 Tornado + Tsunami β Destruction 15 Earth + Fire β Lava 16 Lava + Water β Stone 17 Lava + Stone β Obsidian 18 Destruction + Obsidian β Nether 19 Water + Water β Lake 20 Earth + Earth β Mountain 21 Lake + Mountain β Fjord 22 Water + Wind β Wave 23 Earth + Wave β Sand 24 Sand + Water β Beach 25 Beach + Lava β Hawaii 26 Hawaii + Wind β Hula 27 Hula + Water β Hula Hoop 28 Plant + Wave β Seaweed 29 Hawaii + Seaweed β Poke 30 Plant + Poke β Pokemon 31 Hula Hoop + Pokemon β Hoopa 32 Fjord + Hoopa β Unown 33 Nether + Unown β N 34 Earth + Wind β Dust 35 Lake + Plant β Lily 36 Dust + Lily β Angel 37 Fire + Water β Steam 38 Fire + Steam β Engine 39 Engine + Plant β Car 40 Car + Car β Truck 41 Angel + Truck β UPS 42 Engine + Steam β Train 43 Train + Wind β Zephyr 44 Delta + Zephyr β Zeta 45 UPS + Zeta β Upsilon 46 N + Upsilon β Nu 47 Fire + Wind β Smoke 48 Smoke + Water β Fog 49 Dust + Fog β Smog 50 Fire + Smog β Pollution 51 Pollution + Water β Acid 52 Acid + River β PH 53 Lake + Water β Ocean 54 Ocean + Water β Fish 55 Plant + Smoke β Incense 56 Earth + Fjord β Land 57 Incense + Land β Sage 58 Fish + Sage β Philosopher 59 PH + Philosopher β Phi 60 Nu + Phi β Nucleophile 61 Letters + Nucleophile β Nucleotide
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Nucleotide at a glance
Steps to craft 61 Marathon
Crafting depth 101 longer than 100% of solved elements
Known recipes 1 only one way
Used in 0 other combinations Other elements that take 61 steps Similar effort to Nucleotide, if you want something else to chase.
Frequently asked questions How do you make Nucleotide in Infinite Craft? Combine Letters with Nucleophile. The full path from the base elements takes 61 steps.
How many steps does it take to make Nucleotide? 61 steps on the shortest known path from Water, Fire, Wind and Earth.
Is Nucleotide hard to make in Infinite Craft? It rates as marathon. At 61 steps it is longer than 100% of solved elements.
Is there more than one way to make Nucleotide? Only one known combination produces Nucleotide.
Path verified against the open recipe graph on 2026-10-23 . Method described in our methodology , data credited on data sources .